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WEBUnderstanding the Role of Autophagy in Infectious Disease. The Scientist | 1 min read. Josephine Thinwa shares her journey to becoming a physician scientist and how this led her to investigate the role of a neurologically important kinase in virus-induced autophagy.
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WEBDNA-Sensing Enzyme Wins the 2024 Lasker Award. Laura Tran, PhD | Sep 19, 2024 | 7 min read. Zhijian “James” Chen received this year’s Albert Lasker Award for discovering cGAS, an enzyme which scopes out DNA-based threats and alerts the immune system.
Insights into qPCR: Protocol, Detection Methods, and Analysis
WEBNov 8, 2023 · qPCR, also known as real-time PCR, is an extension of traditional PCR, where DNA amplification over time is quantitated by measuring fluorescence from dyes intercalating into nascent DNA strands or by cleavage of target-specific probes. Therefore, the method combines detection with amplification, providing researchers with crucial …
How Many Genes Do Humans Have? | TS Digest | The Scientist
WEBApr 1, 2024 · In 2004, Human Genome Project researchers published the full and estimated that the human genome contained between 20,000-25,000 genes. Scientists now estimate that the number of protein-coding genes is but that number still fluctuates because the definition of a gene is up to interpretation. A gene is a unit of inheritance, passed from …
Universe 25 Experiment | TS Digest | The Scientist
WEBMay 28, 2024 · John B. Calhoun led the Universe 25 experiment, which examined the long-term effects of increasing population density and resulting social stressors on mice living in a constructed environment. 2. How many times was the Universe 25 experiment repeated? Universe 25 was one long-term experiment in a series of mouse studies.
An Introduction to Glycoproteins | The Scientist Magazine®
WEBJul 18, 2023 · Glycoproteins are a large and diverse group of proteins to which one or more sugar molecules, known as oligosaccharides, have been attached through covalent bonding. These diverse proteins have a wide range of functions, including roles in immune response activation, cell signaling, and disease processes. More than 50 percent of …
What Does a Positive Covid Test Look Like? - The Scientist …
WEBMay 10, 2024 · ABOVE: A positive rapid test will yield two visible lines (middle) while a valid negative test will only show a single line in the control region (right) and an invalid test will show no control line (left). iStock, ASIFE V iral TikTok videos showing teenagers hacking rapid COVID-19 tests by inserting sodas and other acidic solutions into the tests’ inlet …
The Cre- loxP System: A Powerful Tool in the Genetic Toolbox
WEBDec 4, 2023 · Sternberg pondered about the underlying mechanism; he suspected that there must be a genetic hotspot for recombination located at the terminal ends of the linear genome to facilitate plasmid cyclization. 1 . The genesis of Cre-loxP recombinationConsistent with his hypothesis, Sternberg’s experiments revealed a small …
Infographic: The Cre-lox System Explained
WEBDec 4, 2023 · C re-loxP recombination allows scientists to excise, insert, or invert specific DNA segments with unprecedented accuracy. 1,2 This works through two key components: a Cre recombinase and loxP sequence recognition sites. The Cre enzyme identifies pairs of loxP sites (arrowheads), which flank (flox) the DNA, and catalyzes reciprocal DNA …
Words for Nerds - Science Wordle Game - The Scientist Magazine®
WEBWelcome to Words for Nerds, our popular and addictive daily science word game. Think of it as science Wordle—a guessing jumble for every nerd, especially the busy life scientist looking to get a little break from the rigors of research. You have six chances to guess either a five-letter or six-letter (see “Hard Mode” under the settings ...