It follows daytime attacks from both sides, with Israeli strikes in Tehran continuing and Iran firing more missiles towards Israel.

Iran has told mediators Qatar and Oman that it is not open to negotiating a ceasefire while it is under Israeli attack, an official briefed on the communications told Reuters on Sunday, as the two foes launched fresh attacks and raised fears of a wider conflict.

The path to diplomacy appeared to narrow after officials called off talks that had been set for Sunday between Tehran and Washington on the future of Iran’s nuclear program. Israel said the goal of the powerful strikes it unleashed on Friday was disabling Iran’s nuclear infrastructure.

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Israeli Prime Minister Benjamin Netanyahu is on the mission of his lifetime. For years, the veteran leader has made the destruction of Iran’s nuclear program his top priority.

Israel forces have repeatedly hit Iran’s defenses. Prime Minister Benjamin Netanyahu said on Sunday that Israel had worked to “peel off the layers of protection” of Iranian defenses.

Israel's airstrikes have deepened a climate of fear within Iran, where there is a shortage of reliable information. A woman in Tehran said one of the worst things about the attacks is that they usually come without warning.