How chromatin responds to transcription-blocking DNA lesions is unclear. This study reveals that RNA polymerase II (RNAPII) ...

As for chromatin 3D structure, BMI1s have been reported to maintain the compartment domains (CDs) generally, but the mechanism by which they function remains elusive.

Aging is accompanied by widespread epigenetic reprogramming, including the loss of heterochromatin and altered chromatin-associated processes. These changes compromise transcriptional precision and ...

A new study by Dr. Tian Ye's group from the Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of ...

The histone proteins, in conjunction with the chromatin, constitute the nucleosomes. 1 When the N-terminal tails of histone undergo acetylation or methylation, alterations in chromatin structure ...

Naganand Rayapuram, Mai Jarad, Hanna M. Alhoraibi, Jean Bigeard, Aala A. Abulfaraj, Ronny Völz, Kiruthiga Gayathri Mariappan, Marilia Almeida-Trapp, Maria Schlöffel, Emmanuelle Lastrucci, Ludovic ...

A new study on dogs found that chromatin's spatial structure has a significant role in the evolution of social behavior.

Its programmability and versatility make it a powerful tool for studying the spatiotemporal organization of the genome, offering unprecedented insights into chromatin structure and function.

Vesilut, a synthetic dipeptide composed of glutamic acid and aspartic acid (Glu-Asp or ED), has emerged as a molecule of ...

Cancer biology is a dynamically evolving field that continually seeks to unravel the complexities of tumorigenesis and metastasis. Despite advancements in ...