In terms of efficiency, the phosphoramidite method used for synthesizing DNA oligonucleotides is hard to top. Each base-adding step achieves a 99.5% yield. But the method still can’t produce sequences ...

Combining MAGE with CAGE allowed the genome to manipulated as an editable and evolvable template. Scientists have combined a recently developed technique known as multiplex automated genome ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, No. 24 (Dec. 15, 1993), pp. 11538-11542 (5 pages) As an early stage of plant transformation by Agrobacterium ...

HUH endonucleases contain the characteristic HUH motif (in which U represents a hydrophobic residue) and a Y motif, containing either one or two Tyr residues. HUH ...

Genetic change plays a critical role in the adaptation and evolution of bacteria. By acquiring new genes and traits, bacteria ...

Branched polyethylenimine (PEI) chains with an average molecular mass of 2 kDa (PEI2) have been covalently attached to gold nanoparticles (GNPs), and the potency of the resulting PEI2-GNPs conjugates ...

The presence of mobile genetic elements, such as plasmids, transposons, and integrons, greatly enhances the frequency of HGT.

Antibiotic resistance is widely recognized as one of the most urgent public health challenges of the twenty first century.