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A research team has successfully identified a novel DNA damage repair pathway in human cells. This study is the first to ...
A new study shows that the DNA repair enzyme Polβ plays a vital role in protecting the developing brain from harmful ...
An aging expert thinks humans can live for 20,000 years—and he might not be crazy. There's one major key to unlocking extreme ...
“Repair of genetic damage is coordinated in the context of chromatin, so cells dynamically modulate accessibility at DNA breaks for the recruitment of DNA damage response (DDR) factors,” the ...
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Genetic mutations which cause a debilitating hereditary kidney disease affecting children and young adults have been fixed in patient-derived kidney cells using a potentially game-changing DNA ...
To repair double-strand breaks in DNA, homologous DNA sequences must find each other. According to Minsky and colleagues, random diffusion of DNA molecules is too slow for timely repair of these ...
When DNA is damaged, a cell stops dividing and recruits “lifeguard proteins” and repair proteins to get its life cycle back on track. The first microscope was invented almost 500 years ago, when two ...
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Scientists discovered that a well-known DNA repair pathway, the Fanconi anemia pathway, surprisingly plays a key role in repairing double-strand DNA breaks created by CRISPR-Cas9. It acts as a ...
Preserving its DNA ought to be a cell’s top priority. But bacteria slow their DNA repair to a crawl in favor of proofreading gene transcripts.
A new class of DNA repair enzyme has been discovered which demonstrates that a much broader range of damage can be removed from the double helix in ways that biologists did not think were possible.