Homologous recombination is a DNA repair mechanism that counteracts double-stranded breaks in DNA. Researchers at Kindai University have recently revealed how the Sae2 protein coordinates with the ...

DNA repair is essential for the maintenance of genomic stability and its failure can lead to human disease. Various DNA repair systems exist, such as base excision repair, nucleotide excision repair, ...

Failure to repair DNA damage can result in DNA lesions and mutations that are a driving factors in cancer development. Recent work has identified a function for DNA damage repair mechanism beyond ...

When an SSB appears, polymerase epsilon approaches the nick before retracing its steps thanks to its exonuclease, allowing fork reversal to take place. The nick is repaired as an SSB, and replication ...

A research team has unveiled a crucial mechanism that helps regulate DNA damage repair, with important implications for improving cancer treatment outcomes. The result was published in Cell Death & ...

A novel technology combined with optical tweezer C-trap technology gives researchers new insight into DNA repair mechanisms. Researchers at the University of Pittsburgh (PA, USA) have developed a ...

Researchers from Rice University and St. Jude Children’s Research Hospital in Memphis, Tennessee, took a close look at one of the ways cells repair broken strands of DNA and discovered details that ...

Naked mole-rats are one of nature's most extraordinary creatures. These burrowing rodents can live for up to 37 years, around ten times longer than relatives of a similar size. But what is the secret ...

Better understanding of the mechanisms involved in DNA repair may pave the way for developing inhibitors to improve the effectiveness of radiation therapy. Nucleotide excision repair (NER) is a ...

(Nanowerk News) A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA. Such mistakes are frequent in code-copying process in ...

Scientists used magnetic tweezers to reveal how the RNA molecule ‘NIHCOLE’ repairs cell damage, hindering cancer treatments such as radiotherapy. If you want to defeat an enemy, one strategy you can ...