Unexpected slowdowns or spikes in this signal were often interpreted as knots in DNA. But now, a new study published Aug. 12 ...

A new AI tool reveals how tangled DNA knots impact health and disease, offering insights for drug discovery and genetic ...

A new study has found that ORC plays a broad, unexpected role in regulating human cell gene expression and chromatin ...

At school, it's often presented as a tidy double helix but scientists are revealing the varied and intricate shapes of DNA ...

Directed evolution is usually a laborious process that often takes weeks in which proteins rapidly evolve and develop ...

Postmitotic myotubes cannot complete DNA replication following forced cell cycle reactivation. Comparative genomic ...

DNA damage that causes replication forks to stall can be bypassed via translesion synthesis (TLS). New work has identified a bifunctional human primase and TLS polymerase, PrimPol, that ...

Researchers at the University of California, Davis, have just reported a small but significant accomplishment: catching the replication of a single DNA molecule on video for the first time. And ...

Scientists reported a novel molecular mechanism for the regulation of PCNA cycling during DNA replication. They proved that ATAD5-RLC opens PCNA ring to be removed from DNA as a bona-fide PCNA ...

By looking into the mechanism of a backward enzyme, scientists speculate why DNA replication always happens in the forward direction. The team speculate that the reverse-direction enzyme is not ...

You were formed from a single cell. To build you, and then keep you alive, the DNA in your cells needs to undergo replication every day to duplicate your chromosomes before cell division. Decades ...