In ExIGS, expansion microscopy is integrated with in situ genome sequencing to simultaneously sequence genomic DNA and image nuclear proteins at nanoscale resolution within single cells.

Our cells produce a variety of proteins, each with a specific role that, in many cases, means that they need to be in a ...

In 1957, just four years after Francis Crick and other scientists solved the riddle of DNA’s structure—the now famous double ...

DNA’s chemical cousin, RNA, was the messenger that carries DNA instructions from the double helix in the cell’s nucleus to ...

The recoded bacterium uses only 57 of the 64 possible genetic codes, freeing up seven to be used for different purposes ...

You are mostly but not entirely human. If we crunch the numbers, 8% of your genome actually comes from viruses that got ...

Keeping cells healthy The G-loop acts like a landing pad for additional proteins. These proteins untie the G4 knot, break apart the G-loop and convert the DNA to its normal double helix shape.

The fact that thousands of pieces of ancient viruses still exist in the human genome and can even create protein has drawn a considerable amount of attention from researchers, particularly since ...

Scientists are seeking to decipher the role of non-coding DNA in the human genome, helped by a suite of ...

For decades, large stretches of human DNA were dismissed as “junk,” thought to serve no real purpose. In a new study in Cell ...