The specificity of ubiquitin/Ubl-deconjugating enzymes for particular substrates depends on multiple factors, ranging from the topography of specific substrate features, as in different ...

Image Credit: Maltsev Semion / Shutterstock Enzyme-substrate reactions Before enzyme kinetics can be understood it is essential to understand the basics of what enzymes are and how they work.

Thus, enzymes are essential molecular tools of cells to produce their building blocks, but also to regulate their processes. Biological cells contain hundreds of different enzyme and substrate types.

Creative Enzymes provides an array of advanced screening services, including: Substrate Screening: With an extensive library of substrates, researchers can precisely characterize enzyme activity. This ...

For example, if the substrate (the substance upon which the enzyme acts) carries a negative charge, the enzyme could use a negative charge to "stress" the substrate and thus facilitate the reaction.

A team of researchers from the University of Utah and Sethera Therapeutics has uncovered a powerful new way to build more ...

Contrary to what previously thought, enzymes move towards areas with less substrate. They display such behavior despite not having any thinking or sensing capabilities.

Similar defense systems with spatial separation of enzyme and substrate have already been described for other natural products, for example, for glucosinolates, saponins or monoterpenoid indole ...