In eukaryotes, the tight or loose packaging of the genes in chromatin (DNA plus specific proteins) can control whether the genes can be expressed to form their encoded product. Chromatin is usually ...
Researchers at Penn State found that two proteins in the CCR4-NOT complex — CNOT1 and CNOT4 — work in opposition, with CNOT1 encouraging degradation of messenger RNA proteins while CNOT4 slows the ...
“This is the first detailed study of how and where ORC regulates epigenetics and gene expression in human cells,” said Anindya Dutta, Ph.D., leader of the study and chair of the University of Alabama ...
A newly revealed molecular tug-of-war may have implications for better understanding how a multitude of diseases and disorders - including cancers, neurodegenerative diseases and immune disorders - ...
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