Researchers developed a fluorescence quenching assay to probe the integrity of the cell membrane coating of biomimetic nanoparticles (NPs) , discovering that the great majority of the cell membrane ...

Modern bioassays tend to fall under three common modalities: colorimetric, luminometric or fluorometric. Colorimetric assays record the amount of light absorbed by a reporter compound. This absorbance ...

Fluorescent dyes are tools used throughout biotechnology and medicine that offer a unique method of detecting and quantifying the presence of a target molecule, cell, or tissue within an even more ...

SPT Labtech, a global leader in the design and development of automated instrumentation and consumables for life sciences, ...

In a recent study posted to the bioRxiv* pre-print server, a team of researchers used an assay toolset for discovering new transmembrane protease serine 2 (TMPRSS2) inhibiting drug repurposing ...

A direct rate assay for plasminogen activator has been developed using a synthetic fluorogenic peptide substrate, 7-(N-Cbz-glycylglycylargininamido)-4-methylcoumarin trifluoroacetate. The assay ...

Sometimes, toxic side effects aren't discovered until fairly late in the drug development process, when substantial amounts of time and money have already been invested in clinical trials. Even though ...

Adenine and guanine nucleotides are interconverted by diverse proteins of therapeutic interest, including kinases, phosphodiesterases, membrane transporters, DNA-modifying enzymes, and molecular ...

What’s the best method for assessing cell viability? Trypan blue is widely used in cell culture labs for selectively staining dead cells and tissues, but some sample types present challenges for ...

Cell membrane coated biomimetic nanoparticles (NPs) have been widely studied in nanomedicine because of their unique properties such as immune escaping, long blood circulation, specific molecular ...