With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to ...

Researchers at The University of Texas MD Anderson Cancer Center have shown that DNA inflexibility, or rigidity, inside the nucleosome regulates the positioning of INO80. This highlights that the ...

The function of non-coding RNA in the cell has long been a mystery to researchers. Unlike coding RNA, non-coding RNA does not produce proteins -- yet it exists in large quantities. A research team has ...

A newly developed mouse model enables real-time visualization of RNA Polymerase II (RNAP2) during DNA transcription, as ...

The function of a protein can depend on its abundance in a cell. So, when investigating the properties of a new protein, it is essential to make sure that the same amount is produced by every cell.

Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...

Following surgery, patients with breast cancer are faced with the question of whether additional chemotherapy is necessary and really effective. It is important that these women do not receive too ...

As gene therapies continue to advance, the demand for scalable, reproducible, and efficient potency assays is rapidly increasing—especially for adeno-associated virus (AAV) vectors. Accurate ...

When male and female fruit flies age, their brains become desexualized. Age-related changes take place in both sexes, but the male brain becomes feminized to a larger extent than the female brain ...

The goal of gene therapy for patients with hemophilia A is to safely impart long-term stable factor VIII expression that predictably ameliorates bleeding with the use of the lowest possible vector ...