A new study has revealed how HIV squirms its way into the nucleus as it invades a cell. Because viruses have to hijack someone else's cell to replicate, they've gotten very good at it -- inventing all ...

Around one million individuals worldwide become infected with HIV, the virus that causes AIDS, each year. To replicate and spread the infection, the virus must smuggle its genetic material into the ...

At the cellular level, HIV-1 transmission involves a highly coordinated process whereby the virus binds to CD4 receptors and one of two coreceptors—CCR5 (R5) or CXCR4 (X4)—on host immune cells, ...

Researchers at the German Center for Infection Research (DZIF) at Heidelberg University Hospital have decoded a previously unknown mechanism by which HIV-1 selects its integration targets in the human ...

Since its introduction in the late 1980s, HIV antiretroviral therapy (ART) has saved millions of lives by transforming HIV from a fatal disease into a chronic, manageable condition. Despite these ...

CLEVELAND—For over three decades, HIV has played an elaborate game of hide-and-seek with researchers, making treating—and possibly even curing—the disease a seemingly insurmountable obstacle to ...

In the human tragedy of HIV infection, dendritic cells play a vicious double role analogous to an international cocaine trafficker who morphs into a street-level crack peddler. These ...

In individuals who started antiretroviral therapy during acute HIV infection, the proliferative capacity of HIV-specific CD8+ T-cells at 24 weeks of therapy predicted the subsequent reduction in the ...

Scientists are testing CRISPR gene editing as a potential HIV cure after successfully removing the virus from infected cells in lab studies. Here’s what the research means and what comes next.