Origin-recognition complex (ORC) plays an unexpectedly broad role in the regulation of human cell gene expression, according ...

Another DNA structure, called G-quadruplex DNA, was imaged by researchers in human cells in 2013, though the function of those structures is still being explored.

For decades, the Y chromosome — one of the two human sex chromosomes — has been notoriously challenging for the genomics community to sequence due to the complexity of its structure. Now, this elusive ...

Scientists have discovered a new structure inside human cells: a never-before-seen twisted "knot" of DNA. Dubbed the "i-motif," this four-stranded knot looks totally different from the iconic ...

A deeper understanding of how DNA changes over generations helps scientists learn why people differ and how diseases develop. Until recently, many fast-changing parts of the human genome remained ...

“This paper helps us to understand that DNA [is] more than a sequence of letters; DNA is structurally organized, and human variation that structure is important for genomic function and trait ...

For the first time, scientists have detected a DNA structure inside living human cells that looks more like a four-stranded knot than the elegant double helix we learned about in school.

Article Published: 24 June 2010 Structure and mechanism of human DNA polymerase η Christian Biertümpfel, Ye Zhao, Yuji Kondo, Santiago Ramón-Maiques, Mark Gregory, Jae Young Lee, Chikahide ...