Little organs within cells called lysosomes digest unwanted material. And like stomachs, they must be acidic to do so. If they aren't, cells stop growing. Researchers wanted to know why.

New research, published today in the journal Science, shows how lysosomes - organelles that act like cells' waste disposal ...

Those are proteins that break stuff down. Our cells use lysosomes to help destroy germs or recycle old or messed up cell parts. Lysosomes are basically the cell’s trash and recycling centers.

Scientists report that lysosomes in roundworms produce molecules that allow cells to "talk" to one another about aging, coordinating the process across the entire organism.

Co-investigator Nakamura studies obesity and molecular metabolism mechanisms and will use his expertise to study how the enzyme regulates liver metabolism through lysosome function in animal models.

Lysosomes—vital cell organelles—are enzyme-filled subunits found within many animal cells that help break down and reuse macromolecules, such as proteins, lipids, and nucleotides.

Does TMEM175 influence how lysosomes function, too? Indeed, in TMEM175 knockout cells, the lysosomal hydrolase cathepsin B cleaved less fluorogenic substrate. Expression of wild-type TMEM175, but not ...

SARS-CoV-2 Exits Cells Via Lysosomes A study finds that β-coronaviruses don’t use the normal secretory pathway, a possible explanation for some aspects of COVID-19 pathology.