The newly published study takes a hard look at the underlying mechanisms for the DNA mismatch repair (MMR) pathway—which helps maintain genomic fidelity by more than 1000-fold.

Study leader Joanna Loizou adds, "Our results show that the DNA repair pathway, known as mismatch repair, influences prime editing outcomes.

New research discovered a key protein that plays a role in DNA double-strand break repair. MSH2-MSH3, a mismatch repair protein, is recruited to DSB sites through the interaction with a chromatin ...

Research teams have discovered that repair proteins involved in DSB repair, mismatch repair, and TMEJ are closely related and interact with each other during DSB repair process.

Inherited dynamic DNA repeat mutations affect over 30 neurological disorders and several of them also found mismatch repair genes that could affect the repeat instability or disease severity.

DNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role in maintaining genomic stability. The specificity of MMR is primarily for base-base mismatches and ...

This project has reached full capacity for the current term. Please check back next semester for updates. Errors in DNA replication occur at the replication fork, leading to misincorporation events, ...

The 2015 award goes to three scientists who dissected the molecular mechanisms that drive DNA repair.

How DNA repair helps prevent cancer Date: August 16, 2013 Source: University of Texas at Austin, Texas Advanced Computing Center Summary: DNA damage is a natural biological occurrence that happens ...