This new information about how transcription factors work may have implications for RNA-based therapeutics, and has broadened our understanding of how genes activity is regulated. Previous work has ...

While the biology of CTCF has been extensively studied, how the different domains (parts) of CTCF function in relation to transcription regulation remains unclear.

Bacterial transcription is a production line of copying over genetic instructions from double stranded DNA to produce RNA, which is then used for the subsequent production of proteins that the ...

CTCF is a transcription factor that has been a research target due to its role in regulating a critical oncogene called MYC.

They were able to see the transcription enzyme RNA polymerase II (RNAP2) as some of the amino acids making up the enzyme gain phosphate groups (and are phosphorylated). Three steps in the ...

Eukaryotic transcription is a complicated business. The regulation of gene expression is fundamental to cell survival and its study forms the basis of numerous research programmes. Recent ...

DNA’s chemical cousin, RNA, was the messenger that carries DNA instructions from the double helix in the cell’s nucleus to ...

In 1957, just four years after Francis Crick and other scientists solved the riddle of DNA’s structure—the now famous double ...

Dendrobium officinale, a prized medicinal herb, is valued for its bioactive mannans—compounds with documented antioxidant ...

Lacra Bintu discusses how synthetic transcription factors can be used to control gene expression and epigenetic memory.

Ankylosing spondylitis (AS) is increasingly recognized as an independent risk factor for premature myocardial infarction (MI) ...