Results reported in the Journal of Clinical Investigation have identified Vad1, a DEAD-box RNA helicase, as a putative global virulence regulator in Cryptococcus neoformans. The authors used a random ...

A pathogen's ability to infect or damage its host tissues is determined by the virulence factors. These are often molecules synthesized by bacteria or viruses and encoded in their genome, but they may ...

C. neoformans is a fungal pathogen that causes meningitis, which causes approximately 180,000 deaths annually worldwide. Currently, AmB is the only fungicidal drug available to treat fungal meningitis ...

Scientists at Duke University say they have sequenced the entire genome and all the RNA products of the most important pathogenic lineage of Cryptococcus neoformans, a strain called H99. Their study ( ...