RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are ...

RNA splicing ribozymes have been shown to possess a conserved active site that can engage small molecules, opening possibilities for the control of gene expression.

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are ...

Explore the future of healthcare with gene therapies that offer hope for untreatable diseases and advanced treatment options.

RNA splicing involves the removal of non-coding introns and the joining of coding exons in precursor mRNA (pre-mRNA) to produce mature messenger RNA (mRNA). Splicing changes can lead to diseases ...

Although the regulation of splicing factors affects hematopoiesis, the role of dysregulated RNA splicing in clonal blood disorders (such as myelodysplastic syndromes (MDS) and other blood cancers ...

Researchers identified messenger RNA that is missing in pediatric high-grade glioma tumors but not in normal brain tissues.

Merck KGaA has swooped into a neurological-focused pact with RNA biotech Skyhawk Therapeutics that could top out at $2 ...

Defects in RNA processing can promote cancer -- but the mutated proteins responsible can be hard to target. Fred Hutch Cancer Center and Memorial Sloan Kettering Cancer Center scientists discovered a ...