A region of DNA that codes for a protein, often referred to as a gene, is the fundamental unit of heredity responsible for specific traits and functions within an organism. This intricate segment of ...

Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing ...

Researchers discovered that embryos must clear maternal mRNAs to develop properly. When cleanup fails, it causes aberrant transcription and R-loop formation, which blocks DNA replication, damages the ...

You don't want to miss this! To permanently access this eBook for free, fill out the short form below. From being a promising yet underexplored approach in the 1990s, mRNA therapeutics have evolved ...

Messenger RNA (mRNA) technology came of age during COVID-19 with several vaccines and therapeutics coming to market. However, since the height of the pandemic, the flow of new mRNA-based products has ...

Programmed responses to external stimuli and stress allow cells to adapt to changing environmental conditions, and are critical for cellular survival. mRNA transcription by RNA polymerase II (Pol II) ...

Translocation: The ribosome moves one codon down the mRNA. The tRNA in the A site moves to the P site, the tRNA in the P site ...

A new study at Hebrew University reveals insights into mRNA regulation during embryonic development. The study combines single-cell RNA-Seq and metabolic labeling in zebrafish embryos, distinguishing ...

This study presents a valuable tool named TSvelo, a computational framework for RNA velocity inference that models transcriptional regulation and gene-specific splicing. The evidence supporting the ...