Unexpected slowdowns or spikes in this signal were often interpreted as knots in DNA. But now, a new study published Aug. 12 ...

Scientists report the most detailed account yet of the very first steps in DNA replication, an event that all life uses to grow and reproduce Peer-Reviewed Publication ...

The first step in DNA replication requires the assembly of a group of proteins called the Origin Recognition Complex (ORC). Researchers have determined how the ORC assembles during the cell ...

The manipulation of DNA replication and the adoption of advanced gene-editing technologies illustrate a remarkable convergence of scientific innovation and ethical considerations.

These extracts contain almost everything found inside a real cell, especially proteins needed for DNA replication and repair. This setup allowed the team to introduce DNA with G4 structures and ...

To improve replication, the scientists also reported the development of a system capable of evolving polymerases to better recognize 3FB in DNA.

“This is the first step of the mechanism that prompts the enzyme for resolving DNA entanglements,” Lamour said. “DNA gyrase, now surrounded by a tightly supercoiled loop, will cut one DNA helix in the ...