KEY POINTS Acute aortic syndrome (AAS) is a life-threatening emergency, accounting for 1/2000 presentations of acute chest or back pain to the emergency department. [1] [1] It is a clinical spectrum ...

An important flaw in the funding approach used by Canada’s public drug plans is highlighted by the findings of 2 articles related to the clinical value of direct oral anticoagulants (DOACs), published ...

Jacqueline M. McMillan, Elizabeth Aitken and Jayna M. Holroyd-Leduc The appropriate assessment and management of chronic insomnia is crucial. Insomnia affects quality of life and has been shown to be ...

We do a very poor job of health workforce planning in Canada, in large part because of inadequate health workforce data. Inadequate health workforce data have economic costs because poor data limit ...

Wernicke encephalopathy is a medical emergency with substantial morbidity and mortality A historical case series reported mortality in 17% of patients with acute Wernicke encephalopathy. 2 Of the ...

In its 2015 Quality of Death Index report, the Economist Intelligence Unit ranked Canada 11th in overall quality of death and 18th in availability of palliative care services.1 For efforts to develop ...

Background: Cancer surveillance data are essential to help understand where gaps exist and progress is being made in cancer control. We sought to summarize the expected impact of cancer in Canada in ...

Since late 2023, new outbreaks have been reported in Bolivia, Brazil, Peru, and Cuba, including among travellers returning to Canada and the United States. [1] [1], [2] [2] Malaria, Zika, dengue, and ...

Background: Fragility fractures are a major health concern for older adults and can result in disability, admission to hospital and long-term care, and reduced quality of life. This Canadian Task ...

Smoking marijuana can increase clearance of some drugs Smoked marijuana increases the clearance of theophylline 40%. 1 Similar findings would be expected for other drugs metabolized by CYP1A2, such as ...

Figure 1: This figure shows 3 categories of out-of-distribution data, all in the context of training a machine-learned algorithm to read adult chest radiographs (see image C iii). A) Images that are ...

Background: Operative vaginal delivery (OVD) is considered safe if carried out by trained personnel. However, opportunities for training in OVD have declined and, given these shifts in practice, the ...