Israeli officials tell Axios Israel will launch a "significant retaliation" to Iran's massive missile attack within days.

The low-boil conflict between Israel and Iran has shaped the Middle East for decades. Of the many conflicts that have roiled the region, theirs has long been among the most explosive. The two have attacked each other — mostly quietly and in Iran’s case often by proxy — while avoiding an escalation into direct war.

As missile strikes between Israel and Iran continue to make global headlines, more than 400 Wyoming National Guard soldiers and airmen continue

The Middle East moved closer to a long-feared regional war the day after Iran fired a barrage of missiles at Israel and Israel said it began limited ground incursions into Lebanon targeting the Iran-backed Hezbollah militia.

White House officials say they are closely coordinating on possible Iranian targets but have been blindsided repeatedly by Israeli Prime Minister Benjamin Netanyahu.

ANALYSIS: The region, and Western nations, will be hoping to see tensions simmer down, writes Chris Stevenson – but given the leaders involved, that may br a forlorn hope

Netanyahu’s ruthless strategy sets off a wave of retribution that could drag the U.S. into a showdown with Iran, and risks a broader war

The British weekly "The Economist" warns that Israel may activate a 20-year-old plan to attack Iran's nuclear installations. As a pretext, it may use the fact that it was fired upon by Iranian missiles.