Gut

CD48 is a novel immune checkpoint on tumour‐associated macrophages in hepatocellular carcinoma

Background Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality with limited therapeutic options. Despite ...
Gut

Recovery of HBV-specific B cell function after discontinuation of nucleos(t)ide analogue therapy: new insight and future challenges

In hepatitis B virus (HBV) infection, the capacity to mount a functional virus-specific T-cell response has long been considered the principal, if not the sole, immunological determinant of viral ...
Opinion
GutOpinion

Road to IBD prevention in the Global South: a conceptual framework modelling from non-communicable diseases

IBD is rising worldwide and is now a global disease. With the expanding armamentarium of medical therapies, including biologics and small molecules, there is a decline in hospitalisation rates and IBD ...
Gut

Proton pump inhibitors use and risk of inflammatory bowel disease in children

A recent randomised controlled trial showed that proton pump inhibitors (PPIs), compared with histamine-2 receptor antagonists (H2RAs), induce greater gut microbiome alterations and oral-to-gut ...
Gut

Role of A2 beta casein in milk-induced eosinophilic oesophagitis: novel in-vivo and in-vitro findings

We read with interest the article by Santacroce about personalised medicine in eosinophilic oesophagitis (EoE) and the ...
gut.bmj

Individualised therapy is more cost-effective than dose intensification in patients with Crohn’s disease who lose response to anti-TNF treatment: a randomised, controlled trial

4 Department of Hepatology and Gastroenterology V, Aarhus Hospital, Aarhus, Denmark 5 Department of Gastroenterology, Hvidovre Hospital, Hvidovre, Denmark 6 Department of Medical Gastroenterology S, ...
gut.bmj

Nutrient regulation of human intestinal sugar transporter (SGLT1) expression.

Institute of Biological Sciences, University of Wales, Aberystwyth, Ceredigion. BACKGROUND: The activity of most intestinal nutrient transporters is adaptively regulated by the type and amounts of ...
gut.bmj

Guidelines on the management of common bile duct stones (CBDS)

The last 30 years have seen major developments in the management of gallstone-related disease, which in the United States alone costs over 6 billion dollars per annum to treat. Endoscopic retrograde ...
gut.bmj

Deep mural injury and perforation after colonic endoscopic mucosal resection: a new classification and analysis of risk factors

Objectives Perforation is the most serious complication associated with endoscopic mucosal resection (EMR). We propose a new classification for the appearance and integrity of the muscularis propria ...
gut.bmj

What to do about the leaky gut

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be ...
gut.bmj

Severe clinical outcomes of COVID-19 associated with proton pump inhibitors: a nationwide cohort study with propensity score matching

Objective The adverse effects of proton pump inhibitors (PPIs) have been documented for pneumonia; however, there is no consensus regarding whether the use of PPIs might be harmful regarding the risk ...
gut.bmj

Once daily high dose probiotic therapy (VSL#3) for maintaining remission in recurrent or refractory pouchitis

1 Departments of Medicine, Surgery, and Pathology, St Mark’s Hospital, London, UK 2 Departments of Internal Medicine, Gastroenterology, and Surgery, University of Bologna, Bologna, Italy Background: ...