Background Existing scales for assessing faecal incontinence have not been validated against clinical assessment, or with regard to reproducibility. They also fail to take into account faecal urgency, ...
Inflammatory bowel disease (IBD) is typically diagnosed after the onset of symptoms in the context of established, characteristic patterns of intestinal inflammation. However, there is now substantial ...
Objective To present comparative data about the performance of colorectal cancer (CRC) screening programmes in the European Union Member States (EU MSs). Design Cross-sectional study. We analysed key ...
Objective Endoscopic full-thickness resection (EFTR) is a novel treatment of colorectal lesions not amenable to conventional endoscopic resection. The aim of this prospective multicentre study was to ...
Objective To appraise the evidence that pathophysiological mechanisms and individualised treatment directed at those mechanisms provide an alternative approach to the treatment of patients with ...
2 Zhejiang Provincial Key Laboratory of Pancreatic Disease, Hangzhou, China Background Intrahepatic cholangiocarcinoma (ICC) is a highly aggressive malignancy with limited treatment options and poor ...
Background Acute appendicitis is a local intestinal inflammation with unclear origin. The aim was to test whether bacteria in appendicitis differ in composition to bacteria found in caecal biopsies ...
2 Institute of Digestive Disease and the Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong ...
Dr S Blum, Department of Immunology, Nestlé Research Centre, Vers-Chez-les-Blanc, Ch-1000 Lausanne 26, Switzerland. Email: stephanie.blum-sperisen{at}rdls.nestle.com BACKGROUND AND AIM Intestinal ...
Objective The antiviral efficacy of nucleos(t)ide analogues whose main limitation is relapse after discontinuation requires long-term therapy. To overcome the risk of relapse and virological ...
Background Liver failure is the most critical outcome of end-stage liver diseases, with a 28-day mortality rate in the acute phase ranging from 25% to 84% due to a narrow therapeutic window. Liver ...
Correspondence to Dr Michael J Bourke, Department of Gastroenterology and Hepatology, Westmead Hospital, Westmead 2145, New South Wales, Australia; michael{at}citywestgastro.com.au Background and aims ...