BACKGROUND: Evaluation of whether dyspnea has a cardiac cause is essential. Guidelines from 2016 were reported to result in a ...

Research studies in cardiovascular epidemiology assessing the relationship between a primary exposure and a health outcome must account for the presence of what are often called third variables, ...

Cardiovascular disease (CVD) is the predominant cause of death globally, accounting for ≈30% of deaths each year. 1 The prevalence of CVD among adults (aged ≥20 years) in the United States was 48.6% ...

BACKGROUND: Penetrance and risk of ventricular arrhythmias (VAs) in arrhythmogenic right ventricular cardiomyopathy (ARVC) are increasingly recognized as being genotype specific. Therefore, ...

Alcohol is one of the most commonly consumed substances in the world, exhibiting complex relationships with multiple aspects of cardiovascular health and disease. The majority of the research on the ...

Mitral regurgitation (MR) and tricuspid regurgitation (TR) are the most common valvular heart diseases (VHDs) in patients with heart failure (HF). 1–8 Their prognostic role has been established, 2,4,6 ...

In European ancestry populations, a meta-analysis of prospective studies demonstrated a monotonic dose–response association of higher levels of Lp(a) with higher risk of CHD, 2 with concordant ...

MESA is a population‐based, prospective cohort study funded by the National Institutes of Health and the National Heart, Lung, and Blood Institute. 28 Previous publications have provided extensive ...

The effect of these interrelated, sometimes competing and sometimes complementary, trends on clinical practice in the United States has not been clearly defined. In this issue of the Journal, Stehlik ...

More than 20 000 infants and children have a cardiac arrest per year in the United States. 1–4 In 2015, emergency medical service–documented out-of-hospital cardiac arrest (OHCA) occurred in more than ...

Over the past decade, new research has advanced scientific knowledge of neurodevelopmental trajectories, factors that increase neurodevelopmental risk, and neuroprotective strategies for individuals ...

As clinicians delivering health care, we are very good at treating disease but often not as good at treating the person. The focus of our attention has been on the specific physical condition rather ...