Office vacancy levels improved in the San Jose area but worsened in both Oakland and San Francisco in the second quarter of ...

Ten people have been displaced after a building fire broke out in San Francisco’s South of Market district Tuesday morning, according to the San Francisco Fire Department. Firefighters responded just ...

CIF NorCal 6-A football championship: South San Francisco’s incredible season ends, but optimism abounds.

Firefighters responded to a house fire Friday afternoon and were able to save one home but the other was too severely damaged for the residents to return home, according to to the South San Francisco ...

Read reviews by dealership customers, get a map and directions, contact the dealer, view inventory, hours of operation, and dealership photos and video. Learn about Cadillac of South San Francisco ...

South San Francisco’s new skate park doesn’t look like much. There are no half pipes or handrails or complicated obstacles. It’s just a long stretch of flat ground with rectangular ledges ...

South San Francisco police released footage of a chaotic shootout involving a 60-year-old man who was fatally shot by an officer after opening fire on police and a neighbor’s home.

Authorities have responded to South San Francisco High School to investigate a report of an active shooter.

South San Francisco, which touts itself as “the Birthplace of Biotechnology,” now has millions of square feet of approved offices and labs on hold. A cooling life science market has put 9 ...