Genentech is planning a massive overhaul of its 207-acre South San Francisco campus that could cost between $3B and $5B by the time the multiphase project is complete, according to the San Francisco ...

Office vacancy levels improved in the San Jose area but worsened in both Oakland and San Francisco in the second quarter of ...

Ten people have been displaced after a building fire broke out in San Francisco’s South of Market district Tuesday morning, according to the San Francisco Fire Department. Firefighters responded just ...

Firefighters responded to a house fire Friday afternoon and were able to save one home but the other was too severely damaged for the residents to return home, according to to the South San Francisco ...

The Industrial City sign in South San Francisco turns 100 years old today. The 65-foot-tall concrete letters on the southern flank of San Bruno Mountain are one of California’s largest examples ...

A 14-year-old South San Francisco High School student was arrested Friday after allegedly stabbing a fellow student during an altercation on campus, according to authorities.

South San Francisco’s new skate park doesn’t look like much. There are no half pipes or handrails or complicated obstacles. It’s just a long stretch of flat ground with rectangular ledges ...

San Francisco is the nation's leading tech-hub and a popular international tourist destination.

Authorities have responded to South San Francisco High School to investigate a report of an active shooter.

After entitling a huge South City lab and office project late last year, Prologis is back with a new application for another project.