Researchers have discovered how unstructured segments of surface proteins regulate the biological function of a cell. Their ...
Scientists have identified a potential target for a new class of drugs that could effectively treat psychiatric disorders, ...
The reported cryo-EM imaging of a pentameric ligand-gated ion channel in liposomes as opposed to nanodiscs has both broad implications and contributes valuable methodological advances to the ...
Version of Record: This is the final version of the article. The authors, Dalal, et. al., determined cryo-EM structures of open, closed, and desensitized states of the pentameric ligand-gated ion ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Neurotransmitter receptors are critical for ...
Pelthos plans to launch ZELSUVMI™ for the treatment of Molluscum contagiosum infections in July 2025 Concurrent with the closing of the merger, Ligand has invested $18 million in the combined company ...
The brain’s cerebellum plays a key role in coordinating movement, balance, and cognition. Injury to the cerebellum can have a profound impact on basic motor skills, such as sitting, standing, and ...
Moe-Lange, Jacob; Gappel, Nicoline M.; Machado, Mackenzie; Wudick, Michael M.; Sies, Cosima S. A.; Schott-Verdugo, Stephan N.; Bonus, Michele; Mishra, Swastik ...
Cobra venoms are enriched with toxins of low molecular mass, known as three-finger toxins (Panel A). Some of these are neurotoxins, which bind with high affinity to the nicotinic cholinergic receptors ...
Rinatabart sesutecan (Rina-S) for patients with advanced endometrial cancer: First disclosure from dose expansion cohort B2 of the GTC1184-01 study. This is an ASCO Meeting Abstract from the 2025 ASCO ...
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