Oman’s foreign minister says the fifth round of indirect talks between Iran and the United States will be held Friday in Rome.

Iran's Supreme Leader Ayatollah Ali Khamenei slamm ed U.S. demands that Tehran end its uranium enrichment program, stating that he does not believe ongoing nuclear negotiations with the U.S. will yield results. Iran says its nuclear program is for civilian purposes and that its enrichment program is a source of national pride and not negotiable.

The latest round of high stakes nuclear talks between Iran and the US have ended, with Tehran calling them difficult but with both sides agreeing to further negotiations.

A US media outlet reports that Israel may be poised to strike Iran’s nuclear sites and oil markets wince. In Washington, a Republican administration wonders if Tehran is more determined or deterred.

While rising U.S.-Iran tensions over Tehran's uranium enrichment jeopardize nuclear talks, three Iranian sources said on Tuesday that the clerical leadership lacks a clear fallback plan if efforts to resolve a decades-long dispute collapse.

Iran's ratification of a 20-year pact with Russia marks a major step in expanding military and economic ties amid tensions with the West

New intelligence obtained by the United States suggests that Israel is preparing to strike Iranian nuclear facilities, CNN reported on Tuesday, citing multiple U.S. officials familiar with the matter.

Oil prices slipped on Tuesday as traders weighed the impact on supply from Russia-Ukraine peace talks and US-Iran negotiations, strong front-month physical demand in Asia and a cautious outlook for China's economy.