Background Post-infection disorders of gut-brain interaction (PI-DGBI) are a subset of chronic gastrointestinal disorders triggered by acute infectious gastroenteritis. These conditions impose a ...
Early detection and interception of pancreatic ductal adenocarcinoma (PDAC) remain the only realistic strategies to reduce ...
In chronic hepatitis B virus (HBV) infection, the central debate remains whom and when to treat. The 2025 European Association for the Study of the Liver (EASL) Clinical Practice Guidelines (CPGs)1 ...
Background IBD is characterised by recurrent flares, but evidence on whether modifiable dietary factors influence flare risk ...
Primary biliary cholangitis (PBC) is a rare chronic autoimmune cholangiopathy that mainly affects middle-aged women, ...
Background Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disease worldwide. Epidemiological evidence indicates that MASLD is associated with an ...
Background RNA 5-methylcytosine (m5C) has emerged as a critical epigenetic regulator in cancer biology, yet its role in the tumour immune microenvironment (TME) remains incompletely understood.
Background Both host and microbe metabolism of tryptophan (Trp) is altered in diabetes; however, the molecular mechanisms are ...
Correspondence to Professor Hong Cai and Professor Yang Ke, Laboratory of Genetics, Peking University Cancer Hospital and Institute, Beijing 100142, China; drhcai{at}gmail.com, keyang{at}bjmu.edu.cn ...
Objective Given significant advances in treatment of viral hepatitis and the growing epidemic of obesity, the burden of the different types of liver diseases in the USA may be changing. Our aim was to ...
1 Cancer Research UK Colorectal Cancer Unit, St Mark’s Hospital, Harrow, Middlesex HA1 3UJ, UK 2 Wolfson Unit for Endoscopy, St Mark’s Hospital Most colon cancers are assumed to have a premalignant ...
Background: Crohn’s disease (CD) is a chronic relapsing inflammatory bowel disorder. Both biological and psychosocial factors may modulate the illness experience. Aim: The aim of this study was to ...
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