We would like to offer some critical observations regarding the recent article published on the environmental impact of ...

The scanning electron microscope is capable of 25 mμ resolution combined with a great depth of focus, features which make the technique of value in the study of the intestinal mucosa. Surgical ...

Introduction Ustekinumab (UST) has been shown to induce and maintain clinical response and remission and to produce clinically meaningful endoscopic improvement in patients with moderate-severe ...

Objective Over half of patients with IBS have either diarrhoea (IBS-D) or a mixed stool pattern (IBS-M). The relative efficacy of licenced pharmacological therapies is unclear in the absence of ...

Background and aims: The success of Helicobacter pylori eradication regimens depends on gastric pH, inflammation, and mucus thickness. Our aim was to investigate the effects of acid secretion, ...

Peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear receptor that regulates intestinal inflammation. PPARγ is highly expressed in the colon and can be activated by various dietary ...

Non-alcoholic fatty liver disease (NAFLD) has rapidly become the most common chronic liver disease globally and is currently estimated to affect up to 38% of the global adult population. NAFLD is a ...

1 Department of Internal Medicine, National Nagasaki Medical Center, Omura, Nagasaki, Japan 2 Second Department of Internal Medicine, Nagasaki University School of Medicine, Sakamoto, Nagasaki, Japan ...

Correspondence to Dr Silvio Danese, Gastroenterology and Gastrointestinal Endoscopy Unit, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milano, Lombardia, Italy; ...

The Lyon Consensus provides conclusive criteria for and against the diagnosis of gastro-oesophageal reflux disease (GERD), and adjunctive metrics that consolidate or refute GERD diagnosis when primary ...

Correspondence to Dr Johann von Felden, Department of Internal Medicine, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany; j.von-felden{at}uke.de; Dr Augusto Villanueva, Liver Cancer Program, ...

Systemic messenger RNA replacement therapy is effective in a novel clinically relevant model of acute intermittent porphyria developed in non-human primates ...