A 40-year-old man presented to the emergency department with a 5-day history of fevers, sore throat, fatigue, subjective ...

Whether extended lymphadenectomy is associated with improved disease-free and overall survival, as compared with standard lymphadenectomy, among patients with localized muscle-invasive bladder ...

The next U.S. president will inherit multiple epidemics with inequitably distributed effects. Kamala Harris and Donald Trump are likely to take divergent policy approaches to addressing these crises.

CAR T-cell manufacturing involves T-cell apheresis, CAR transduction, and expansion of transduced autologous or allogeneic T cells. To date, approved CAR T-cell products rely on lentiviral ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when ...

Outcomes of elections for the presidency and Congress and in the states could have profound effects on the coverage available to tens of millions of Americans. From New York University, New York ...

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A data sharing statement provided by the authors is available with the full text of this article at NEJM.org.

From the Department of Health Care Policy, Harvard Medical School, and the Division of General Internal Medicine and Primary Care, Brigham and Women’s Hospital — both in Boston (J.M.M.); and ...

A 26-year-old man presented with a 1-week history of fevers and bloody stools. A CT scan of the pelvis showed rectal thickening, and a flexible sigmoidoscopy showed nodular, ulcerated mucosa.

On the basis of 28 national opinion polls, the authors summarize Democrats’ and Republicans’ views on health policy issues and discuss the implications of the 2024 election outcome for U.S ...