Rapid pathogen detection is crucial for effective disease management, particularly in bloodstream infections. Current molecular diagnostics often require nucleic acid preamplification, adding time and ...

Edited by Scott Hultgren, Washington University in St. Louis School of Medicine, St. Louis, MO; received March 7, 2024; accepted January 27, 2025 ...

Contributed by Gurudev S. Khush; received May 27, 2024; accepted July 26, 2024; reviewed by Paul Christou and Götz Hensel In line with intensified efforts to combat the multifaceted impacts of ...

Contributed by Chi-Ming Che; received October 6, 2023; accepted April 27, 2024; reviewed by Harry B. Gray and Yi Lu ...

Contributed by Ian J. Bateman; received April 20, 2024; accepted October 3, 2024; reviewed by Roy Brouwer, Catherine L. Kling, and Marije Schaafsma This contribution is part of the special series of ...

Healthy brain function requires a delicate balance of neural excitation (E) and inhibition (I). In animals, this balance—the E/I ratio—is known to decrease with the maturation of inhibitory circuitry ...

This work was supported by Ludwig Institute for Cancer Research core funding (Y.S.) and an endowed professorship by the Icahn School of Medicine at Mount Sinai (J.J.). This work utilized the NMR ...

We show that for thousands of years, humans have concentrated in a surprisingly narrow subset of Earth’s available climates, characterized by mean annual temperatures around ∼13 °C. This distribution ...

This work was supported by the National Key R&D Program of China (No. 2023YFD1400800) and the Zhejiang Key Research and Development Program of China (Nos. 2020C02001 ...

We previously reported two classes of reproductive phasiRNAs (phased, small interfering RNAs) in maize, the premeiotic 21-nt (nucleotides) phasiRNAs and the meiotic 24-nt phasiRNAs. Here, we report a ...

Recent experiments have challenged the belief that glial cells, which compose at least half of brain cells, are just passive support structures. Despite this, a clear understanding of how neurons and ...

Edited by Danielle Basset, University of Pennsylvania, Philadelphia, PA; received May 2, 2024; accepted January 28, 2025, by Editorial Board Member Elizabeth A. Buffalo ...