Genentech is planning a massive overhaul of its 207-acre South San Francisco campus that could cost between $3B and $5B by the time the multiphase project is complete, according to the San Francisco ...

Office vacancy levels improved in the San Jose area but worsened in both Oakland and San Francisco in the second quarter of ...

Working on the steep slopes below San Bruno Mountain, workers apply paint to a 60-foot tall “S” letter, part of the “South San Francisco The Industrial City” sign, Tuesday, Sept. 19, 2023.

Ten people have been displaced after a building fire broke out in San Francisco’s South of Market district Tuesday morning, according to the San Francisco Fire Department. Firefighters responded just ...

A word of warning if you're moving to South San Francisco: Normally, the welcome mat is out. It's been out since the late 1800s, when hard-working immigrants from Ireland, Portugal, Germany ...

Firefighters responded to a house fire Friday afternoon and were able to save one home but the other was too severely damaged for the residents to return home, according to to the South San Francisco ...

SOUTH SAN FRANCISCO – A big mixed-use project in South San Francisco that will include a new Safeway store is pushing ahead with a real estate company’s purchase of a choice site for the development.

The first update of South San Francisco’s General Plan in nearly a quarter century is expected to be completed this summer, a three-year effort that stands to open up more pockets of the city to ...

A 14-year-old South San Francisco High School student was arrested Friday after allegedly stabbing a fellow student during an altercation on campus, according to authorities.

South San Francisco’s new skate park doesn’t look like much. There are no half pipes or handrails or complicated obstacles. It’s just a long stretch of flat ground with rectangular ledges ...